Synthesis of Novel Biologically Active Mono Acid Esters Derived From The Constituents of Urtica Pilulifera
- Publication Type
- Original research
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New mono acid esters have been synthesized from the reaction of benzoic acid and mono-hydroxybenzoic acids with 2-phenoxyethanol separated from Urtica pilulifera, characterized, and screened for possible antioxidant, antifungal, antimicrobial and anticancer activities. 2-phenoxyethyl 4-hydroxy benzoate showed considerable activity against MCF-7 with IC50 is less than 62.5 µg/ml, and complete inhibition at a concentration less than 37.5 µg/ml against M. canis and less than 50 µg/ml against T. rubrum. On the other hand 2-phenoxyethyl 2-hydroxy benzoate reveals 70% of gentamicin against K. pneumoniae.
Journal
- Title
- Iranian journal of pharmaceutical research (IJPR) 01/2013; DOI:ID: 5287-IJPR
- Publisher
- --
- Publisher Country
- Palestine
- Publication Type
- Both (Printed and Online)
- Volume
- --
- Year
- 2014
- Pages
- --