This study focuses on the development of a composite based on polylactic acid (PLA) and treated hydroxyapatite (HApt). The use of poly-caprolactone (PCL) as an adjuvant has significantly improved the resistance and the rigidity of the composite, which could extend the physico-chemical and biological applications of this material. The amount of PCL needed to optimize the traction and physico- chemical properties of the membranes were evaluated. Several methods for the preparation of different types of composites were developed. The transmission electron microscopy (SEM) analysis results showed a textural uniformity of the membranes. The physico-chemical studies have allowed providing mechanisms of interactions between composites phases.