Fowl adenoviruses (FAdVs) associated with inclusion body hepatitis (IBH) was identified in
5 commercial broiler chickens in Palestine. Investigated birds showed primary clinical signs and
6 lesions of IBH include growth retardation congested and enlarged liver with necrosis, petechial
7 hemorrhage, and basophilic intranuclear inclusion bodies. The mortality rate was from 15%. The
8 FAdV was detected and sequenced in the liver samples of the infected chicken by polymerase
9 chain reaction (PCR) using hexon gene-specific primers. Phylogenetic analysis revealed that
10 FAdVs belongs to FAdV-D serotype 10, clustered within the European highly pathogenic
11 isolates. The highest nucleotide sequence similarity was 99.48 % with highly pathogenic FAdV-
12 D serotype 10 detected from infected chicken in Poland 2010 (GenBank: LN907532.1) and
13 FAdV-D (GenBank: HE961828.1) from infected chicken in Sweden. The lowest similarity was
14 93.46% with Canadian FAdV-D (GenBank: EF685576.1). In conclusion, this is the first report
15 that describes the presence of IBH and reveals that the causative virus is closely similar to the
16 highly pathogenic FAdV-D serotype 10 of IBH in broiler chickens in Palestine.
 

Title

Veterinary Research Forum

Publisher

Faculty of Veterinary Medicine, Urmia University

Publisher Country

Iran

Indexing

Thomson Reuters

Impact Factor

0.7

Publication Type

Both (Printed and Online)

Volume

12

Year

2021

Pages

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