Course Title

Medicinal chemistry II

Course Number

7303302

Instructor Name

Mohammed Hawash

Contact Information

[email protected]

Semester(s) and academic year(s)

Second Semester 2026
Second Semester 2025
Second Semester 2024
Second Semester 2023
Second Semester 2022
Second Semester 2021

Compulsory / Elective

Compulsory

In the beginning of course, a drug design and development subject will be covered then a study of certain classes of drugs and their mechanism of action and their structure activity relationship will be followed. Drugs to be studied include anti-cancer drugs, cholinergic and adrenergic system, diuretics, cardiovascular diseases drugs (antihypertensive drugs, Antianginal Drugs, Anticoagulants, Antihyperlipidimic Agents),   opioids, histamine and antihistamines, CNS drugs, and finally Antidiabetic Agents.

1. illustrate the Principles of Drug Design and Development

2. Analyze the Medicinal Chemistry of Anticancer Agents

3. Explore the Design of Cholinergic and Adrenergic Drugs

4. Study the Chemistry of Cardiovascular Drugs

5. Investigate the Structure-Activity Relationships of H1 and H2 Antagonists

6. Examine the Chemistry of Central Nervous System (CNS) Drugs

7. illustrate the Structure and Chemistry of Anti-Diabetic Agents

1. Illustrate and explain the Principles of Drug Design and Development
2. Evaluate the Chemistry and apply the knowledge of different therapeutic drugs such as the cholinergic and adrenergic drugs, diuretics, opioids, and the H1 & H2  antagonists
3. Analyze the structure-activity relationship of different therapeutic classes, such as anticancer agents, cardiovascular drugs, CNS drugs, and anti-diabetic agents.
4. Collaborate with peers to analyze scientific paper in the development and design of pharmacological active molecules

- An Introduction to Medicinal Chemistry by Graham L. Patrick, fifth edition. Oxford University Press, 2013

- Journal of medicinal chemistry

- ACS medicinal chemistry letters

- European journal of medicinal chemistry