A clinical comparison of corneal staining and comfort associated with contact lens care solutions in Palestine
Publication Type
Conference Paper

There are various contact lens solutions and disinfectant system available in the Palestinian market. Some CL solutions induce staining when combine with hydrogel or silicon hydrogel contact lenses materials which is known as solution induced corneal staining (SICS). This staining attributes to CL discomfortability, ocular redness, photophobia, corneal inflammation and erosions which ultimately leads to patients drop out. It is standard practice to be familiar with the lens-solution interaction prior prescribing CL and its care products to minimize the risks of SICS.


The possible interaction between the commercially available solutions and contact lenses and its potential effect on the ocular surface have not been studied in Palestine. The purpose of this study is to compare the biocompatibility and comfort of 4 lens care solutions currently marketed in Palestine.

A randomized, interventional, single-center crossover study is conducted assessing methafilcon A silicone hydrogel contact lenses, bilaterally, pre-soaked in saline (control) and in the following lens care solutions: Neo plus (containing Polyhexamethylene biguanide hydrochloride), Poly soft plus  (containing Sodium Hyaluronate), Aqua soft (Polyaminopropyl biguanide) and Complete (Polyquaternium-1 & Boric acid). Subjects were randomized to the order of test solution use. For each of the 5 solutions tested, subjects attended a baseline/lens dispensing visit and an intervention visit 2 h later. At both visits, evaluation included corrected-distance visual acuity, slit-lamp examination, corneal staining, and a subjective assessment which includes photophobia, ocular redness, dryness, scratchiness, burning, and stinging.


The results of this study provide evidences if SICS is induced by the use of one of the tested solutions and stresses on the importance of choosing the appropriate CL solution for each patient formerly and discussing the CL compliance, which will therefore minimize the overall risks of solution-induced corneal staining. A series of such studies using different CL material in the Palestinian market will provide guidelines to the eye care practitioners on what to prescribe as a care products when prescribing contact lenses.

Conference Title
4th Jordanian Palestinian Optometry Conference
Conference Country
Conference Date
April 14, 2018 - April 16, 2018
Conference Sponsor
Optometry Syndicate