This research aims to study the Quran’s approach regarding warning from ignorance. This approach has clearly presented through the Quranic texts which implemented sever warning of the ignorance era behavior. The Quran call to reluctant ignorance by describing former infidel Nations with ignorance, as the case of Noah’s people peace be upon him, people of Add (the people of the prophet Hud, and the people of Israel. Finally, the research clarifies the virtuousness of the prophets, peace be upon them from ignorance which is considered as a deviation from the right approach.