Pyrazoles are an important class of five-membered nitrogen heterocycles, which are very
widely used as synthetic scaffolds for the construction of bioactive molecules (Ajay et al.,
2015). Apart from their synthetic utilities, pyrazole derivatives themselves exhibit a broad
spectrum of biological activities (Farghaly et al., 2012). As part of our studies in this area,
we herein report on the crystal structure of the title compound.
The molecular structure of the title compound is shown in Fig. 1. The pyrazole ring
(N1/N2/C1–C3) makes dihedral angles of 39.74 (8) and 60.35 (8) with the phenyl (C8–
C13) and the toluene (C14–C19) rings, respectively. The dihedral angle between the
phenyl and toluene rings is 62.01 (7).
In the crystal, molecules are linked by C—H   interactions, forming chains propagating
along the a axis (Table 1 and Fig. 2).
Synthesis and crystallization
To a solution of (E)-ethyl 2-(4-methylbenzylidene)-3-oxobutanoate (0.01 mol), which
was obtained by our earlier reported procedure (Naveen et al., 2016), and phenylhydrazine
hydrochloride (0.01 mol) in ethyl alcohol (20 ml), 3–4 drops of piperidine were

Title

IUCrData

Publisher

International Union of Crystallography

Publisher Country

United Kingdom

Publication Type

Prtinted only

Volume

1

Year

2016

Pages

1-7