Structural Relationships between the Isoenzymes of Human Placental Alkaline Phosphatase: A Serum Factor Converts M-PLAP to A- And B-PLAP
Publication Type
Original research
Authors
  • Living stone, J.C.
  • Abu-Hasan, N.S.
  • Clegg, R.J.
  • Henderson, S.J.
  • Marsden, H.S.
  • Sutcliffe, R.G.

A protein factor has been found in serum which converts the M form of placental alkaline phosphatase (PLAP) to the A and B forms. The identity of the conversion products has been confirmed by analysis of their dimers and polypeptides. Proteolysis is not implicated in this phenomenon. This report establishes microvillous M-PLAP as the precursor of the A and B forms.   

Journal
Title
Placenta 8, 305-318
Publisher
--
Publisher Country
Palestine
Publication Type
Both (Printed and Online)
Volume
--
Year
1987
Pages
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