4-Hydroxy-2-quinolones. 38. Synthesis, structure, and anticonvulsant activity of optically active 1-phenylethylamides of 1-R-4-hydroxy-2-oxo-3-quinolinecarboxylic acids
- Publication Type
- Original research
- Authors
- Nidal Amin Jaradat
A synthesis is reported for optically pure antipodes of 1-phenylethylamides of 1-R-4-hydroxy-2-oxo-3-quinolinecarboxylic acids. An attempt was made to establish the absolute configuration of these products by X-ray diffraction crystallographic analysis. The anticonvulsant activity of the S-enantiomers was studied.
Journal
- Title
- Chemistry of Heterocyclic Compounds, Volume 36, Number 1 / January, 2000
- Publisher
- --
- Publisher Country
- Palestine
- Publication Type
- Both (Printed and Online)
- Volume
- --
- Year
- 2000
- Pages
- --