Synthesis and characterization of novel 2,2-di(pyridin-2-yl) hexahydropyrimidine and its derivative5,5-dimethyl-1,3- bis[(methylsulfonyl)oxy]-2,2-dipyridin-2-ylhexahydropyrimidine
- Publication Type
- Original research
- Authors
2,2-di(pyridin-2-yl) hexahydropyrimidine heterocyclic compound was prepared by condensation reaction of 1,3- propanediaminewith di(pyridin-2-yl)methanone 1.5,5-dimethyl-1,3-bis[(methyl sulfonyl)oxy]-2,2-dipyridin-2- ylhexahydropyrimidine 2 was prepared by protection of both N-H groups in 2 using MeSO3Cl reagent in
pyridine/THF media.The prepared compounds revealed good thermal stability, and simple one step decomposition mechanism. The condensation reaction to prepare 1has been monitored by IR.The structures of the desired compounds were characterized by elemental analysis, EI-Ms, UV-Vis, FT-IR, TG and NMR.
Journal
- Title
- Der Pharma Chemica
- Publisher
- Scholar research library
- Publisher Country
- United States of America
- Indexing
- Thomson Reuters
- Impact Factor
- 0.58
- Publication Type
- Both (Printed and Online)
- Volume
- 6
- Year
- 2015
- Pages
- 5