An approximate solution of the Schrödinger equation for the generalized Hulthén potential with non-zero angular quantum number is solved. The bound state energy eigenvalues and eigenfunctions are obtained in terms of Jacobi polynomials. The Nikiforov–Uvarov method is used in the computations. We have considered the time-independent Schrödinger equation with the associated form of Hulthén potential which simulate the effect of the centrifugal barrier for any l-state. The energy levels of the used Hulthén potential gives satisfactory values for the non-zero angular momentum as the generalized Hulthén effective potential.