Efficacy of Aqueous and Ethanol Extracts of Some Palestinian Medicinal Plants for Potential Antibacterial Activity
Publication Type
Original research

Nine medicinal plants growing in Palestine were screened in vitro for potential antibacterial activity against 6 bacterial strains by well diffusion and micro-dilution techniques. Both aqueous and organic solvents were used. The dried extracts of Sacropoterium spinosum (Rosaceae) (seed), Ruta chalepensis L (Rutaceae) (leaf), Cassia senna (Ligumenosa) (leaf), Lawsonia inermis (Lythraceae) (leaf), Psidium guajava (Myrtaceae) (Leaf), Carataegus  azerullus (Rosaceae) (Leaf), Ranunclus asiaticus(Ranunculaceae) (Flowers), Calendula officinalis (Composita) (Flowers),and Salvia syriaca (Labiatae) (leaf) were screened. The bacterial strains tested were; Methicillin-resistant Staphylococcus aureus (MRSA); three strains (1, 2 & 3), multidrug resistant Pseudomonas aeruginosa, Proteus vulgaris and Klebsiella pneumonia. The average diameter of inhibition zones ranged from 9 to 30 mm and 11 to 28 mm for aqueous and ethanol extract, respectively. Methicillin-resistant Staphylococcus aureus (MRSA) was the most inhibited microorganism. Sacropoterium spinosum extract was the most active against Methicillinresistant Staphylococcus aureus (MRSA) and multidrug resistant  Pseudomonas aeruginosa. The MIC value of ethanol extract was 0.781 mg/ml  against MRSA while 0.390 mg/ml against Pseudomonas aeruginosa. The  combination effect of ethanol extracts of (Sacropoterium spinosum with  Lawsonia Inermis) on bacterial species tested exhibited a higher effect than  that of any individual extract.  Such results lead to an interesting promise for further investigation to design  potentially active antibacterial augmentative agents of natural sources. 

The Islamic University Journal (Series of Natural Studies and Engineering) Vol.16, No.2, pp 77-86
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Both (Printed and Online)