Recently, wastewater reuse is receiving a great deal of focus and interest among planners and decision makers in the West Bank, Palestine. This interest in wastewater reuse is motivated by the shortage in water resources accessibility due to the unstable political situation in the region. Much of the recent dispute that took place at the national level and among the stakeholders and planners revolved around issues related to the priorities of wastewater reuse in terms of location implementation of reuse schemes. The paper illustrates the conceptual framework for developing such a map and elaborates on the factors that dictate map development. Examples of such factors are discussed. The paper’s outcomes show that the development of the map requires a multi-disciplinary expertise and the work necessitates the collaboration among experts from different fields.