Background: Type 2 diabetes mellitus (T2DM) has been associated with higher perioperative risks in coronary artery bypassgrafting (CABG). This study examines preoperative characteristics, surgical factors, and postoperative outcomes of diabetic andnondiabetic patients undergoing CABG to identify differences in clinical profiles and complications.Methods: A retrospective analysis was conducted on 425 patients (214 nondiabetic, 211 diabetic) using SPSS 21. Continuousvariables were compared using the Student t-test, whereas categorical variables were compared using the chi-squared test.Results: Diabetic patients had higher BMI (30.1 vs. 28.4 kg/m 2 , p < 0.001), worse glycemic control (HbA1c 7.9 vs. 5.6, p < 0.001), and higher rates of hypertension (84.4% vs. 62.6%, p < 0.001) and CHF (73% vs. 64%, p = 0.03). They also exhibited lower he-moglobin levels (12.8 vs. Thirteen.6 g/dL, p < 0.001), higher INR (1.0 vs. 0.9, p < 0.001), and higher rates of STEMI (13.3% vs.5.1%, p = 0.003). Sex distribution also differed, with fewer males in the diabetic group (147 vs. 172, p = 0.007). Surgically, theyrequired more urgent/emergent procedures (27% vs. 7.4%, p < 0.001) and longer bypass times (147.5 vs. 135.2 min, p = 0.024).Postoperatively, diabetics had higher mortality (5.2% vs. 0.5%, p = 0.003), stroke (13.3% vs. 2.8%, p < 0.001); cardiovascular eventssuch as MI or stroke (9% vs. 0.5%, p < 0.001); infections (36.5% vs. 2.3%, p < 0.001); renal failure (20.4% vs. 2.8%, p < 0.001); gas-trointestinal events (17.5% vs. 4.7%, p < 0.001); postoperative cardiac arrest (33.6% vs. 22%, p = 0.005); reoperation for bleeding(9.5% vs. 1.4%, p < 0.001); and longer hospital stays (9.2 vs. 6.3 days, p < 0.001). After adjustment for baseline demographic andclinical characteristics, diabetes mellitus was independently associated with significantly worse postoperative outcomes.Conclusion: Diabetic patients undergoing CABG had worse preoperative health, challenging surgical procedures, and muchworse postoperative outcomes. These findings highlight the importance of targeted perioperative interventions for reducinghazards in this high-risk population.

Title

Biomed Research International

Publisher

Wiley

Publisher Country

United States of America

Indexing

Scopus

Impact Factor

2.9

Publication Type

Prtinted only

Volume

5

Year

2026

Pages

1-16