Background End-stage renal disease is a significant global health issue, and Peritoneal Dialysis (PD) is a vital
treatment modality. The study aims to assess the Quality of Life (QoL) and pain levels in PD patients and explore
potential influencing factors.
Methods A cross-sectional study was conducted in 2022 involving 76 PD patients at a referral tertiary dialysis
center in Palestine. The study evaluated patient demographics, clinical data, laboratory measures, quality of life as
assessed by the KDQOL-SF36, and pain levels as determined by the Brief Pain Inventory. Statistical analyses, including
multivariate linear regression, were employed to identify relevant associations.
Results This study included 76 PD disease patients, with 68.4% being under the age of 60 and 53.9% being
male. Almost one-third of the participants (34.0%) reported mild to severe pain, and 23.7% reported low to high
interference levels. Pain severity was negatively correlated with supplement doses for both vitamin D3 (p = 0.049) and
calcium (p < 0.01). Female patients reported higher pain severity (p = 0.001) and interference (p < 0.007) levels. The
study revealed relatively higher QoL among our cohort of PD patients compared to previously published findings
in similar settings, specifically for HD populations. Factors such as age, comorbid conditions, and duration of dialysis
influenced QoL (p < 0.05). Pain severity and interference were negatively correlated with QoL (p = 0.01).
Conclusion This study provides valuable insights into the QoL and pain experiences of PD patients in Palestine. It
underscores the importance of effective pain management strategies and holistic care to improve QoL in this patient
population. Addressing psychological and emotional well-being is vital for optimizing treatment adherence and longterm
outcomes.

Title

BMC Nephrology

Publisher

Springer Nature

Publisher Country

United States of America

Indexing

Scopus

Impact Factor

2.4

Publication Type

Prtinted only

Volume

26

Year

2025

Pages

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