Rabies is a fatal viral infection with clinical presentation that can mimic other neurological disorders, such as Guillain-Barre Syndrome (GBS). Both conditions can present in early stages with same signs, including muscle weakness and paralysis, leading to diagnostic confusion. In this case report, we present a patient residing in Palestine who was initially diagnosed with GBS but was later found to have rabies. Early diagnosis of rabies is important because once clinical symptoms appear, the disease almost fatal. This case highlights the importance of increased awareness and consideration of rabies in differential diagnoses, especially in areas where the disease is endemic
