Multiple Sclerosis (MS) is an autoimmune disease characterized by recurrent episodes of central nervous
system (CNS) demyelination leading to variable clinical symptoms. The exact etiology and pathogenesis
of the disease still remains unknown; however, it is believed to occur as a result of genetic,
environmental and immunological factors. Change in the size of brain structure is an important issue in
patient with multiple sclerosis (Shambhu Kumar Sah...etc, 2016). Hippocampal atrophy is the main
interested problem in the hippocampus. The aim of the study to find if there’s a relationship between
multiple sclerosis and associated changes in the brain structure (hippocampus and temporal lobe)
which can use later to find if these changes affect patient memory and learning ability.
Magnetic resonance image (MRI) was used to obtain brain images for 5 patients with multiple
sclerosis(3 females and 2 males) according to An –Najah National University Hospital with age
between (18 – 40) and 5 control patients with no neurological history. A T 1 coronal weighted
image were acquired in a1.5 Tesla Philips scanner
The result show that there’s a change in the size of the hippocampus and temporal lobe in patient with
multiple sclerosis compared to the normal patient with the right side of the hippocampus and temporal
lobe have higher percentage of volume lose compared to the left side but in the same time the change
were not so significant and may be as a result of age or other condition related to life style.

Conference Title

7th PFMR Biomedical Research Symposium

Conference Country

Palestine

Conference Date

Oct. 7, 2017 - Oct. 7, 2017

Conference Sponsor

none