This study examines the relationship between Corporate Governance (CG) and the value relevance (VR) of accounting information in companies listed on the Palestine Exchange from 2009 to 2019. The study uses Ohlson’s (1995) model to measure the VR and conducts fixed effect regression analysis to test the study hypotheses. The results show that VR has a significant positive relationship with board size, board ownership, audit committee size, and audit quality. In contrast, a negative relationship was observed between VR and role duality, while no significant relationship existed between board activity and VR. The study highlights the importance of CG practices in enhancing the VR of accounting information and provides recommendations for policymakers, managers, and stakeholders to improve CG practices in Palestine.