Crohn's disease is a chronic inflammatory bowel disease that can affect multiple gastrointestinal tract segments and may lead to intestinal obstruction. Additionally, there is a known association between Crohn's disease and colon cancer. A 42-year-old male with a history of Crohn's disease presented to the emergency department with abdominal pain lasting one month. The patient was diagnosed with intestinal obstruction, and a differential diagnosis for colon cancer was considered due to overlapping symptoms. Following the biopsy, colon cancer was confirmed. Therefore, it is recommended that any patient with Crohn's disease presenting with signs of intestinal obstruction be evaluated for possible colon cancer.