One of the hallmarks in the advancement of cancer cells is an ability to overcome and acquire resistance to adverse conditions and thereby, become immortal. The search for anti-cancer drugs with minimal side effects has led to the discovery of synthetic molecules with anti-carcinogenic activity. One reason cancer cells escape apoptosis is down regulation of tumour suppressor genes and appearance of oncogenes. Impairment of this native defense mechanism of cancer cells promotes anomalous cellular proliferation and the accumulation of genetic defects, eventually resulting in tumorigenesis and resistance towards cancer drugs.

Title

Ismail Warad

Publisher

Ismail Warad

Publisher Country

Palestine

Publication Type

Prtinted only

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Year

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