This paper described the experience of developing a MOOC at An Najah National University and how it was transferred into a SPOC from the perspective of its team developers. Learners' responses and participation had been analyzed in order to understand its content. The data collected described the motivation for developing the MOOC and then using it as a SPOC, in addition to presenting the challenges that face its development and implementation. The development of the MOOC Genetic and Society at An Najah National University went through different stages starting from offering the course to students face to face and then developing the course online and then preparing it as a MOOC, finally using it as a SPOC to student university. The findings showed the main motives for developing the MOOC such as the well to increase the online Arabic content in this area. The main challenge that faced the course designers was the lack of technical support. The paper recommends developing more MOOCs in different languages in the medical field.