Introduction Herbal medicine has been useful in the treatment of various diseases and has played a critical role in the discovery of new drugs. This study aimed to investigate the phytoconstituents, antioxidant, antidiabetic and antiobesity activities of the traditional medicinal plant, Echium angustifolium Mill. Methods The constituents of E. angustifolium four solvents fractions were established utilizing conventional analytical methods. Antioxidant, antilipase, anti-glucosidase, and anti-α-amylase activities of E. angustifolium were conducted using DPPH (1, 1-diphenyl-2-picrylhydrazyl α), p-nitrophenyl butyrate, P-NPG (4-nitrophenyl β-d-glucopyranoside), and dinitrosalicylic acid procedures, respectively. Results The methanolic fraction of E. angustifolium displayed inherent antioxidant properties with an IC 50 value of 1.95 μg/mL. Moreover, the hexane fraction presented potential α-amylase inhibitory activity with an IC …

Title

European Journal of Integrative Medicine

Publisher

Elsevier

Publisher Country

United Kingdom

Indexing

Thomson Reuters

Impact Factor

0.97

Publication Type

Online only

Volume

38

Year

2020

Pages

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