SYNTHESIS AND BIOLOGICAL ACTIVITIES OF A NOVEL NARINGIN BASED HETEROCYCLIC DERIVATIVES
Publication Type
Conference Paper
Authors

A number of naringin based heterocyclic derivatives dioxolane and imidazolidine have been synthesized and evaluated for their antioxidant and biological activities. The chemical structures of newly synthesized

compounds were verified on the basis of spectral and elemental methods of analysis. Investigation of antibacterial activity of these compounds was determined by measuring MIC value using broth micro dilution method for Gram-positive and Gram-negative bacteria, among the various synthesized compounds. Dioxolane showed the highest antibacterial activity with minimal inhibitory concentration (MIC) of 0.125mg/ml, in addition this compound exhibit the best antioxidant activity with inhibition concentration (IC50) of 18.7 μg/mL, compared with other semi synthetic derivative.

Conference
Conference Title
IX Palestinian international chemistry conference
Conference Country
Palestine
Conference Date
Nov. 1, 2019 - Nov. 2, 2019
Conference Sponsor
Bethlehem University
Additional Info
Conference Website