Diabetes Mellitus in Patients with Schizophrenia in West-Bank, Palestine
نوع المنشور
بحث أصيل
المؤلفون
النص الكامل
تحميل
  • Abstract

    Aims

    The main aims of the study were to investigate the prevalence of pre-diabetes and diabetes mellitus (DM) in patients with schizophrenia, to compare it with those published in the general population, and to assess significant associations with dysglycemia defined as having either pre-DM or DM.

    Methods

    A cross-sectional study carried out in 4 governmental primary psychiatric healthcare centers in Northern West-Bank, Palestine. Fasting blood glucose (FBG) and glycated hemoglobin (HbA1c) were measured. The World Health Organization (WHO) criteria for defining pre-DM and DM were used. Dysglycemia was defined as FBG >110 mg/dl.

    Results

    Based on WHO criteria, 27 patients (10.8%) had diabetes and 34 (13.6%) had pre-diabetes. The prevalence of DM in patients with schizophrenia was not significantly higher than that reported in the general population of Palestine. However, the prevalence of pre-DM was significantly higher than that reported in the general population of Palestine. Regression analysis showed that advancing age and abnormal waist circumference were significant predictors of dysglycemia in patients with schizophrenia.

    Conclusions

    This study confirmed the high prevalence of dysglycemia in patients with schizophrenia, supporting the need for monitoring of blood glucose in this category of patients. The presence of primary risk factors is more important in the development of dysglycemia in patients with schizophrenia than exposure to antipsychotic drugs.

المجلة
العنوان
Diabetes Research and Clinical Practice Volume 99, Issue 3, March 2013, Pages 351–357
الناشر
Elsevier
بلد الناشر
أيرلندا
Indexing
Thomson Reuters
معامل التأثير
3,369
نوع المنشور
Both (Printed and Online)
المجلد
99
السنة
2013
الصفحات
351-7