Abstract

A new Schiff base N'-( (5-bromothiophen-2-yl) methylene ) nicotinohydrazide wasisolated andcharacterizedasZ-isomer as seen in the Scheme.

The synthetic condensation reaction was monitored by FT-IR and UV- visible as well as DFT calculation. The structure of desired compound was experimentally analyzed based on: elemental analysis, EI-Ms, UV-visible, FT-IR

spectral, TG/DTG. 1H-NMR and DFT-computational calculation supported Z- isomer as favorited product over E one. Good agreement between experimental and theoretical calculatation were obtained. The antibacterial results obtained using the desired compound indicates a promising result against human pathogenic bacteria.

Keywords: FT-IR, condensation, TG, Schiff bases, DFT.

عنوان المؤتمر

Second Palestinian International Conference on Material Science and Nanotechnology (PICNM2016)

دولة المؤتمر

فلسطين

تاريخ المؤتمر

23 مارس، 2016 - 24 مارس، 2016

راعي المؤتمر

An Najah National University