موظفي النجاح

نوع المنشور

بحث أصيل

المؤلفون

Assem Barakat , Abdullah M. Al-Majid Mohammad Shahidul Islam Vijay H. Masand M. Iqbal Choudhary , Ismail Warad , Sammer Yousuf
Ismail Warad
اسماعيل وراد

النص الكامل

تحميل

Trimolecular salt Michael adducts 2a–c were synthesized in excellent

yields up to 92 % via one-pot multicomponent reactions in an aqueous medium. The

chemical structures of compounds 2a–c were characterized by X-ray single-crystal

diffraction techniques. Calculations of the density functional theory for the synthesized

compound were performed. The stability of the products was deduced by

TGA analysis. Compounds 2a–c were screened in vitro for different bio-assays such

as thymidine phosphorylase inhibition assay, urease inhibition assay, b-glucuronidase

inhibition assays and cytotoxicity against PC-3 and HeLa cell lines.

المجلة