Pyridlhydrazone derivatives [1-5] were synthesized for the first time by condensation of di-2-pyridyl ketone with different hydrazides individually. The corresponding solid phase hydrazide-hydrazones were collected from acidic-ethanolic medium after 8-10 hours of reflux in very good to excellent yields and purified twice by ethanol/water re-crystallization process. All the synthesized compounds are characterized by IR, 1H and 13C NMR, FAB-MS and other physical analyses tests. The microbiological antifungal activity was carried out toward Trichophyton mentagrophytes, Microsporum canis and Trichophyton rubrum.

العنوان

Journal of Saudi Chemical Society

الناشر

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بلد الناشر

فلسطين

نوع المنشور

Both (Printed and Online)

المجلد

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السنة

2007

الصفحات

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