Objective: To evaluate the possible in vitro interaction between ethanolic extracts of Rhus coriaria (R. coriaria) (seed), Sacropoterium spinosum (S. spinosum) (seed), Rosa damascena (R.damascene) (flower) and certain known antimicrobial drugs including oxytetracycline HCl,pweansi ccialrlirnie Gd ,o cuetp ahgaaleinxsint ,3 s ucllfiandicimale sthtroaxiinnse oafs msoudltiiudmru, ga-nrde seinstraonflto xPasceiund. oTmhoisn assy naeerrguyg sintuodsay (P. aeruginosa).
Methods: Evaluation of synergy interaction between plant extracts and antimicrobial agents was carried out using microdilution method.
Results: The results of this satnudd yte ssht oawnetdim thicarto tbhiearle a igse an tdse. cTrehaes em ions tt hien tMerIeCs tiinn gc arsees uolft cwomasb tihnaatt iothne o cf oemthbainnoaltiico np labnett wexeterna cRts.coriaria and these antibiotics, showed a high decrease in minimum inhibitory concentration (MIC),and a strong bactericidal activity against these strains.
Conclusions: These results may indicate that combinations between R. coriaria extract and these antibiotics could be useful in fighting emerging drug-resistance P. aeruginosa, which may due to that R. coriaria extract contain natural iunnhdiebriwtoarys wleoardkiinngg tboy t hdeif fiedreenntti fmiceacthioann iosfm tsh eo ra icnthivieb imtinogle ecfuflluesx ppruemsepnst. Nino wR . wceo rhiaarviea .e xFpuerrthimere,n itns vivo experiments are needed to confirm pseudomonal protection.

العنوان

Asian Pacific Journal of Tropical Medicine, Volume 3, Issue 4, Pages 266-269

الناشر

Elsevier

بلد الناشر

الصين

Indexing

Thomson Reuters

معامل التأثير

1,225

نوع المنشور

Both (Printed and Online)

المجلد

3

السنة

2010

الصفحات

266-269