Introduction: The objective of the present study was to report, for the first time, the presence of canine parvovirus type 2c (CPV-2c) indomesticated dogs with acute gastroenteritis and to characterize the antigenic variants circulating in Palestine.Methodology: A veterinary clinical-based epidemiological study was carried out between December 2022 and April 2023. Fifty fecal sampleswere collected from dogs with gastroenteritis and screened for CPV-2 infection by polymerase chain reaction. The distribution of positive casesaccording to various epidemiological factors was studied. Partial sequencing of the viral protein 2 (VP2) gene was performed for the analysisof CPV-2 variants.Results: Most of the investigated samples (60%; n = 50) during the study period were found positive for CPV-2 infection. There was nodifference in the distribution of positive cases of CPV-2 infection based on age group, gender, location, and vaccination status. The analysis ofnucleotide and amino acid sequences from amplified products, as well as phylogenetic analysis, revealed the presence of CPV-2c clusteredwith Asian CPV-2c variants.Conclusions: In summary, this study represents the initial genetic analysis of CPV-2 present in Palestinian dogs with gastroenteritis andprovides evidence that confirms the existence of the CPV-2c variants. To determine the prevailing CPV-2 variant associated with the infection,it is crucial to conduct further sequence analysis using large populations of both domestic and wild canines

العنوان

The Journal of Infection in Developing Countries https://jidc.org

الناشر

Journal of Infection in Developing Countries

بلد الناشر

إيطاليا

Indexing

Scopus

معامل التأثير

0,401

نوع المنشور

إلكتروني فقط

المجلد

18

السنة

2024

الصفحات

809-816