The intricate and dynamic ecosystem of microorganisms residing in the human gastrointestinal tract, collectively known as the gut microbiome, has emerged as a central player in human health and disease (Ley et al., 2006). This complex community, comprising trillions of bacteria, archaea, viruses, and fungi, does not merely exist in a passive commensal relationship with the host (Guo et al., 2025). Instead, it engages in a continuous, bidirectional crosstalk, profoundly influencing host physiology, metabolism, and immunity (Li et al., 2021; Liu et al., 2023). Among the myriad factors shaping the composition and function of the gut microbiome, diet stands out as one of the most potent and modifiable (Koh et al., 2016; Sonnenburg and Bäckhed, 2016).
