Varthemia iphionoides is indigenous to Palestine, where it is traditionally being used for treatment of gastrointestinal disorders. The aim of this paper was to provide pharmacological validation to this medicinal use. Water and ethanol extracts of Varthemia iphionoides were studied on isolated rabbit ileum for spasmolytic action. These extracts showed a reduction of the amplitude and the tone of spontaneous contraction in a concentration-dependent manner. Apart from that, water extract of Varthemia iphionoides drastically diminished the increase of the contraction of the ileum caused by acetylcholine (ACh) concentration of 5.5X10-6M. This indicates that Varthemia iphionoides extract probably acts at least through muscarinic receptors blockade.

العنوان

Journal of Pharmacy Research 4(12),4367-4368

الناشر

Journal of Pharmacy Research

بلد الناشر

الهند

Indexing

Scopus

معامل التأثير

None

نوع المنشور

Both (Printed and Online)

المجلد

4

السنة

2011

الصفحات

4367-4368