Background Metabolic dysfunction-associated steatotic liver disease (MASLD) is the leading cause of liver disease globally, closely associated with metabolic syndrome.
Objectives This study aimed to identify significant predictors of metabolic syndrome in patients with MASLD.
Methods A retrospective cross-sectional study was conducted on adult type 2 diabetes mellitus (T2DM) patients
between January 2018 and April 2022. Of 314 initially collected patients, those without MASLD or with other liver
diseases were excluded, leaving 240 MASLD patients for analysis. Metabolic syndrome was assessed using the NCEP
ATP III criteria, and data analysis was performed using Stata17.
Results Higher systolic blood pressure (adjusted OR = 1.000427, p < 0.0001) and larger waist circumference
(adjusted OR = 1.001517, p < 0.0001) were independently associated with increased odds of metabolic syndrome.
Additionally, higher triglyceride levels (adjusted OR = 1.064834, p < 0.0001) and lower HDL cholesterol levels (adjusted
OR = 0.998595, p = 0.003) were significant predictors. Other variables, including age, HbA1c, BMI, LDL, and hepatic
steatosis index, were not significantly associated with metabolic syndrome after adjusting for confounders.
Conclusion Higher systolic blood pressure, larger waist circumference, elevated triglyceride levels, and lower HDL
cholesterol levels are significant predictors of metabolic syndrome in MASLD patients.
Keywords Metabolic dysfunction-associated steatotic liver disease, MASLD, Metabolic syndrome, Waist
circumference, Systolic hypertension, Triglyceride, High-density lipoprotein

العنوان

BMC Gastroenterology

الناشر

BMC Gastroenterology

بلد الناشر

المملكة المتحدة

Indexing

Scopus

معامل التأثير

None

نوع المنشور

Both (Printed and Online)

المجلد

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السنة

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الصفحات

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