Introduction: The objective of the present study was to report, for the first time, the presence of canine parvovirus type 2c (CPV-2c) in  
domesticated dogs with acute gastroenteritis and to characterize the antigenic variants circulating in Palestine.  
Methodology: A veterinary clinical-based epidemiological study was carried out between December 2022 and April 2023. Fifty fecal samples  
were collected from dogs with gastroenteritis and screened for CPV-2 infection by polymerase chain reaction. The distribution of positive cases  
according to various epidemiological factors was studied. Partial sequencing of the viral protein 2 (VP2) gene was performed for the analysis  
of CPV-2 variants.  
Results: Most of the investigated samples (60%; n = 50) during the study period were found positive for CPV-2 infection. There was no  
difference in the distribution of positive cases of CPV-2 infection based on age group, gender, location, and vaccination status. The analysis of  
nucleotide and amino acid sequences from amplified products, as well as phylogenetic analysis, revealed the presence of CPV-2c clustered  
with Asian CPV-2c variants.  
Conclusions: In summary, this study represents the initial genetic analysis of CPV-2 present in Palestinian dogs with gastroenteritis and
provides evidence that confirms the existence of the CPV-2c variants. To determine the prevailing CPV-2 variant associated with the infection,  
it is crucial to conduct further sequence analysis using large populations of both domestic and wild canines.

العنوان

Journal of Infection in Developing Countries

الناشر

University of Sassari

بلد الناشر

إيطاليا

Indexing

Thomson Reuters

معامل التأثير

1,9

نوع المنشور

Both (Printed and Online)

المجلد

18

السنة

2024

الصفحات

809-816