Abstract

In clinical practice, physicians have recently attempted to avoid mechanical ventilation (MV) as much as possible and have started to use non-invasive ventilation (NIV) in patients with respiratory failure. A prospective observational study was conducted to assess the applicability, effectiveness, and safety of NIV in managing patients with respiratory failure in Palestine. Fifty-two patients (39 patients from West Bank and 13 patients from Gaza Strip) who fulfilled criteria for inclusion were admitted to the two medical care units of the An-Najah National Teaching Hospital during a 10-month period. These patients formed the study population to receive NIV. The results came with baseline (mean ± SD) pH, PaO₂, and PaCO₂ measurements of 7.36 ± 0.1, 75.62 ± 32.7, and 46.5 ± 20.86 mmHg, respectively. The primary indication for NIV was hypoxemic respiratory failure (n = 38, 73%). The success rate with NIV was 78%, with 40 out of 52 patients weaned successfully. Significant improvements were observed in the first hour following institution of NIV in pH (7.38 ± 0.07, P < 0.001), PaO₂ (90.4 ± 52.4, P < 0.001), and PaCO₂ (40.4 ± 12.6, P < 0.001). These physiological parameters continued to improve up to the time of weaning: pH (7.39 ± 0.07, P < 0.001), PaO₂ (99.9 ± 44.3,P < 0.001), and PaCO₂ (38.6 ± 13.9, P < 0.001). The parameters were maintained within 12 h post-weaning: pH (7.39 ± 0.08, P < 0.001), PaO₂ (97 ± 30.3, P < 0.001), and PaCO₂(36.9 ± 10.3, P < 0.001). This study has shown benefits of NIV in avoiding the call for invasive MV in patients exhibiting respiratory failure of varied etiology, with similar results comparable to previous studies in developed countries. Thus, increased usage of NIV in respiratory failure is likely to affect favorably in countries with limited resources such as Palestine.

العنوان

the eygptian journal of critical care medicine

الناشر

the eygptian journal of critical care medicine

بلد الناشر

مصر

نوع المنشور

Both (Printed and Online)

المجلد

--

السنة

--

الصفحات

--