Synthesis of novel aminoisoflavones and their L-alanyl conjugates, for possible use in chromogenic media for the detection of aminopeptidase‏
نوع المنشور
بحث أصيل
المؤلفون

Aminoisoflavones are synthetic derivatives of a group of natural products found in plants and dietary components such as soya derived products. Three novel aminoisoflavones have been prepared via nitration of the parent isoflavone followed by reduction using tin (II) chloride dihydrate. These unstable aminoisoflavones were then conjugated with Lalanine, to give stable derivatives. The instability of the parent suggested that these conjugates could be used in chromogenic media to detect L-alanyl aminopeptidase producing Gram-negative bacteria, as cleavage of the amide would result in decomposition and the production of colored compounds. However, biological evaluation with a series of bacteria were conducted, although a simpler o-aminophenol conjugate did give black colonies with Escherichia coli strains on doped agar plates.

المجلة
العنوان
Journal of Materials and Environmental Sciences
الناشر
University of Mohammed Premier Oujda Morocco
بلد الناشر
المغرب
Indexing
Scopus
معامل التأثير
None
نوع المنشور
Both (Printed and Online)
المجلد
11
السنة
2020
الصفحات
238-246