Free radicals and enzymes inhibitory potentials of the traditional medicinal plant Echium angustifolium‏
نوع المنشور
بحث أصيل
المؤلفون

Introduction Herbal medicine has been useful in the treatment of various diseases and has played a critical role in the discovery of new drugs. This study aimed to investigate the phytoconstituents, antioxidant, antidiabetic and antiobesity activities of the traditional medicinal plant, Echium angustifolium Mill. Methods The constituents of E. angustifolium four solvents fractions were established utilizing conventional analytical methods. Antioxidant, antilipase, anti-glucosidase, and anti-α-amylase activities of E. angustifolium were conducted using DPPH (1, 1-diphenyl-2-picrylhydrazyl α), p-nitrophenyl butyrate, P-NPG (4-nitrophenyl β-d-glucopyranoside), and dinitrosalicylic acid procedures, respectively. Results The methanolic fraction of E. angustifolium displayed inherent antioxidant properties with an IC 50 value of 1.95 μg/mL. Moreover, the hexane fraction presented potential α-amylase inhibitory activity with an IC …

المجلة
العنوان
European Journal of Integrative Medicine
الناشر
Elsevier
بلد الناشر
المملكة المتحدة
Indexing
Thomson Reuters
معامل التأثير
0,97
نوع المنشور
إلكتروني فقط
المجلد
38
السنة
2020
الصفحات
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