Water providers in Palestine are constantly facing deficits between supply and demand, especially in summer periods. Besides, the costs of treating wastewater are becoming a big burden on these providers. On the other hand, construction related industries (ready-mix concrete, building block, precast manholes, and stone crushing plants) are consuming considerable amounts of drinking water. This research aims at assessing the suitability and feasibility of using secondary treated wastewater (STWW) from Nablus-West Wastewater Treatment Plant (NWWTP) in these industries. This could save precious drinking water, reduce the cost of getting rid of treated wastewater, and reduce the production cost in these industries. The suitability of using (STWW) in concrete mixing was experimentally evaluated. Concrete cube specimens were cast using drinking water, and STWW which obtained from NWWTP. The tested concrete cubes were produced inappropriate percentage mix design and the only variable in this mix was water; Twelve cubes were mixed by drinking water and Twelve cubes were mixed by STWW. Both groups of samples were subjected to several tests including Time of Setting of Concrete Mixtures by Penetration Resistance test, slump test, compressive strength test, and density test. Furthermore, chemical analysis for the STWW was performed to check the possibility of corrosion of reinforcement steel. These tests included: chlorides as Cl-, alkalis as (Na2O+0.658 K2O), sulfates as SO4, pH, Chemical Oxygen Demand (COD), Total Dissolved solids (TDS, measured by Electrical conductivity “EC”), Total solids by mass and Total Chlorine. The results showed that STWW can be used for concrete mixing without affecting the compressive strength nor cause corrosion to reinforcement steel. The type of water used for mixing did not affect concrete slump and density.