Course Title

cell biology

Course Number

10201321

Instructor Name

سلوى خلف

Contact Information

[email protected]

Semester(s) and academic year(s)

Second Semester -2

Compulsory / Elective

Compulsory

This course is concerned primarily with eukaryotic cells. Lectures are devoted to structural details and the molecular functions of the different parts of the cell. Lectures will introduce topics such as endocytosis, intramembrane transport, protein targeting, organelle biosynthesis, protein sorting, exocytosis, cell shape, motility, and cell-to-cell interaction. In addition, lectures will deal with signal transduction processes, cell cycle, mitosis, cancer and cellular functions that are required for cell growth and programmed cell death. By its completion, students should have a comprehensive understanding of the architecture and function of living cells

Become familiar with the various sub-cellular structures and organelles inside eukaryotic cells

♦ Understand how proteins and lipids are synthesized, transported and degraded

♦ Learn about vesicular trafficking, endocytosis and exocytosis

♦ Gain an introduction to cellular signal transduction mechanisms (also known as cell signaling)

♦ Become familiar with the molecular structure and behaviors of the cytoskeleton

♦ Understand the basic events of the cell cycle and the importance of programmed cell death (apoptosis)

At the end of this course, the student should be able to

• Describe the chemical components and processes of cells.
• Describe the storage of genetic information within cells and how this information is passed on to the next generation.
• Discuss membrane structure and transport across cell membranes.
• Discuss the different macromolecules structures and functions.
• Describe the significant processes involved in transfer and storage of energy in a cell.
• Describe the significant processes that occur in cell communication and intracellular transport
• Describe the life cycle of cells and how these cycles are regulated.
• Describe the mechanisms involved in gene expression.
• Discuss the different possible causes of cancer, cellular changes at molecular level and the different methods used and proposed for cancer therapy.

Text book:  Becker’s World of the Cell 8^th edition (2016). Hardin, Bertoni and Kliensmith  

References:

1. Becker’s World of the Cell 8^th edition (2012). Hardin, Bertoni and Kliensmith

2. The World of the Cell, 7^th ed (2009), by Becker, Kleinsmith, Harden and Bertoni

3. Becker, Kleinsmith, and Hardin, 2006. The World of the Cell, 6^th ed. Pearson Benjamin Cummings.

4. Becker, Kleinsmith, and Hardin, 2004. The World of the Cell, 5^th ed. Pearson Benjamin Cummings.

5. Gerald Karp, 2008. Cell and molecular Biology; concepts and experiments, 5^th ed. John Wiley and sons.

6. Alberts et al, 2004. Essential Cell Biology, 2^nd ed. Garland Science.

7.  Pollard, T.D. and Earnshaw, W.C. 2002.Cell Biology, 1^st ed. Elsevier Science (USA).

8. Lodish, H. et al. 2002. Molecular Cell Biology, 4^th ed. New York: Freeman and Company.

9. Cooper,G. M., 2000.    The Cell: A molecular approach. 2^nd ed. Washington, D. C. ASM press.